动物医学进展2017，Vol.38Issue(4)：80-83,4.
中药生物碱的提取及抗炎作用研究
Study on the Alkaloid Extract from Traditional Chinese Medicine and Anti-inflammatory Effect
摘要
Abstract
To compare the differences of anti-inflammatory effect among total compound alkaloids,simplified compound alkaloids and alkaloids of Leonurus japonicus of traditional Chinese medicine "GongYanJing" in mice,the mice were divided into five groups including normal saline,dexamethasone,total compound alkaloids,simplified compound alkaloids and alkaloids of Leonurus japonicus.The anti-inflammatory experiments adopted mouse ear swelling model,toe swelling model,celiac capillary permeability experiment and granuloma inflammation model to evaluate the anti-inflammatory effect of each treatment.The results showed tant compared with alkaloids of Leonurus japonicas,simplified compound alkaloids and total compound alkaloids could significantly inhibit rates of xylene-induced ear swelling and albumen-induced toe edema,suppress the hyperplasia of granulation tissue induced by cotton ball,and reduce the capillary permeability in abdominal cavity.However,there were no difference found between simplified compound alkaloids(P<0.05)and total compound alkaloids groups and dexamethasone group(P>0.05).The anti-inflammatory effect of both simplified compound alkaloids and total compound alkaloids of traditional Chinese medicine "GongYanJing" is better clinical medcine.关键词
中药复方宫炎净/生物碱/抗炎效果Key words
traditional Chinese medicine GongYanJing/alkaloid/anti-inflammatory effect分类
农业科技引用本文复制引用
王梦远,郭晓,刘晓婷,商云霞,谷新利..中药生物碱的提取及抗炎作用研究[J].动物医学进展,2017,38(4):80-83,4.基金项目
新疆兵团科技支疆项目(2013AB010) （2013AB010）
