中国耳鼻咽喉头颈外科2017，Vol.24Issue(4)：191-193,3.DOI:10.16066/j.1672-7002.2017.04.007
慢性鼻-鼻窦炎鼻息肉组织及外周血嗜酸细胞与临床表现的关系
Clinical examination of tissue and blood eosinophilia in chronic rhinosinusitis with nasal polyps
摘要
Abstract
OBJECTIVE To analyze the correlation between number of tissue eosinophils(Eos) and blood Eos levels in patients with chronic rhinosinusitis with nasal polyps(CRSwNP), and to investigate if tissue and blood eosinophilia predicts disease severity and prognosis in CRSwNP. METHODS A retrospective analysis of 102 patients, who diagnosed with CRSwNP was carried out in this study. Surgical specimens were evaluated for degree of tissue Eos, which was compared with blood Eos. Patients were divided into two groups according to the results of endoscopy one year after surgery: recurrent and non-recurrent group. Statistical analysis was performed to compare tissue and blood Eos and CT Lund-Mackay scores. RESULTS Blood and tissue Eos in recurrent group was significantly higher than that in non-recurrent group(P=0.032, 0.033, 0.017). There was not a statistical difference of CT scores between two groups(P =0.089). There was a significant correlation between tissue Eos and absolute number of blood Eos(r=0.637, P=0.000) as well as between tissue Eos and percentage of blood Eos(r=0.542, P=0.000). However Eos and CT scores were not correlated statistically(P>0.05). CONCLUSION Blood Eos levels can predict the degree of Eos infiltration in nasal polyps. Blood and tissue Eos correlate with prognosis.关键词
鼻窦炎/鼻息肉/嗜酸细胞Key words
Sinusitis/Nasal Polyps/Eosinophils引用本文复制引用
孙靖雯,张家雄,郑佳谊,蔡晓菁,邹文焘..慢性鼻-鼻窦炎鼻息肉组织及外周血嗜酸细胞与临床表现的关系[J].中国耳鼻咽喉头颈外科,2017,24(4):191-193,3.基金项目
同济大学青年优秀人才(1501219113) （1501219113）
