硅酸盐学报2017,Vol.45Issue(3):393-401,9.DOI:10.14062/j.issn.0454-5648.2017.03.11
羟基磷灰石及其复合材料增材制造研究现状
Additive Manufacture of Hydroxyapatite and Its Composites
摘要
Abstract
Hydroxyapatite (HA), which is similar to inorganic mineral in natural bones, is a main biomaterial for fabricating bone tissue engineering scaffolds due to its superior biocompatibility and bone conductibility. Bone tissue engineering scaffolds show a complex and customised structure, which has a greater requirement for manufacturing processes. However, it is difficult for the conventional manufacturing techniques such as foaming method and injection forming to create an ideal porous scaffold of artificial bones. Additive manufacture (AM) is capable of making any shapes of three-dimensional solid parts layer-by-layer by using computer-aided design models. Compared to the conventional processes, the AM shows some unique advantages in fabricating bone tissue engineering scaffolds with greater manufacturing accuracy, complex external shapes and internal micro-porous structures. This paper reviews the state of the art in the preparation and the AM process of HA and its composite materials, and proposes an outlook in this aspect.关键词
增材制造技术/羟基磷灰石/生物材料/骨组织工程支架Key words
additive manufacturing/hydroxyapatite/biomaterial/bone tissue engineering scaffold分类
机械工程引用本文复制引用
马高,朱伟,史云松,闫春泽,史玉升..羟基磷灰石及其复合材料增材制造研究现状[J].硅酸盐学报,2017,45(3):393-401,9.基金项目
广东省引进创新创业团队计划(2013C071). (2013C071)