神经损伤与功能重建2017，Vol.12Issue(2)：118-121,4.DOI:10.16780/j.cnki.sjssgncj.2017.02.007
误诊为脑炎的神经系统梅毒5例报道及文献回顾
Clinical Characteristics of Patients with Neurosyphilis Misdiagnosed as Encephalitis: Case Report and Literature Review
摘要
Abstract
Objective:To analysis the clinical characteristics of patients with neurosyphilis misdiagnosed as encephalitis and investigate the reasons for misdiagnosis.Methods:The clinical data,laboratory examination,imaging characteristics of five cases were retrospectively analyzed.Related literatures were reviewed to summarize the clinical features of neurosyphilis.Results:Three men and two women were recruited,ageing 35 ～ 78 years old,without HIV infection.Four cases denied the history of syphilis infection.The main symptoms were mental behavior disorder and cognitive dysfunction.CSF revealed increased number of cells and (or) proteins.Cranial MRI studies revealed the lesion in temporal lobe,accompany brain atrophy and hydrocephalus.The serum and cerebrospinal fluid examination of syphilis were positive.After standard treatment of penicillin and ceftriaxone,three cases received good recovery,two cases had poor prognosis.Conclusion:The clinical symptoms of neurosyphilis are complex and varied.It is easily to be misdiagnosed at early stage for lacking typical cerebrospinal fluid and MRI imaging outcome.The data of serum and cerebrospinal fluid of syphilis are helpful for diagnose.关键词
神经梅毒/脑炎/误诊/文献回顾Key words
neurosyphilis/encephalitis/misdiagnosis/literature review分类
医药卫生引用本文复制引用
黄梁江,熊永洁,黄晓江,张苏明..误诊为脑炎的神经系统梅毒5例报道及文献回顾[J].神经损伤与功能重建,2017,12(2):118-121,4.基金项目
深圳市科技计划项目(JCYJ2014050916270497) （JCYJ2014050916270497）
