海南医学院学报2017，Vol.23Issue(7)：907-910,4.DOI:10.13210/j.cnki.jhmu.20170406.047
重症急性胰腺炎患者血清PCT含量与靶器官损伤、炎症反应程度的相关性
Correlation of serum PCT levels with target organ damage and inflammatory reaction degree in patients with severe acute pancreatitis
摘要
Abstract
Objective: To study the correlation of serum PCT levels with target organ damage and inflammatory reaction degree in patients with severe acute pancreatitis.Methods: A total of 146 patients who were diagnosed with acute pancreatitis in our hospital between May 2014 and September 2016 were selected, the patients with mild acute pancreatitis and severe acute pancreatitis were selected as the mild group and severe group, respectively;healthy subjects who received physical examination during the same period were selected as the control group.Serum was collected to determine the contents of PCT, liver and kidney function indexes as well as inflammatory reaction indexes.Results: Serum PCT, sTREM-1, IL-1β, IL-6, IL-8, IL-18 and TNF-α contents of severe group and mild group were significantly higher than those of control group, and serum PCT, sTREM-1, IL-1β, IL-6, IL-8, IL-18 and TNF-α contents of severe group were significantly higher than those of mild group;serum ALT, AST, TBIL, BUN and Scr contents of severe group were significantly higher than those of mild group and control group, and serum ALT, AST, TBIL, BUN and Scr contents of mild group were not significantly different from those of control group;serum ALT, AST, TBIL, BUN, Scr, TREM-1, IL-1β, IL-6, IL-8, IL-18 and TNF-α contents of severe group of patients with high PCT content were significantly higher than those of patients with low PCT content.Conclusions: Serum PCT levels significantly increase in patients with severe acute pancreatitis and on liver and have evaluation value for liver and kidney function damage as well as inflammatory reaction degree.关键词
重症急性胰腺炎/降钙素原/肝功能/肾功能/炎症反应Key words
Severe acute pancreatitis/Procalcitonin/Liver function/Kidney function/Inflammatory reaction分类
医药卫生引用本文复制引用
武可,白晶利,王卫,陈莹,邱洁..重症急性胰腺炎患者血清PCT含量与靶器官损伤、炎症反应程度的相关性[J].海南医学院学报,2017,23(7):907-910,4.基金项目
邯郸市科技局科技研发计划项目(1623108157) （1623108157）
It was supported by Science and Technology Research and Development Project of Science and Technology Bureau of Handan （）
