海南医学院学报2017，Vol.23Issue(7)：932-934,3.DOI:10.13210/j.cnki.jhmu.20170113.003
腹腔镜子宫肌瘤剔除术对子宫肌瘤患者性激素水平的影响
Effect of laparoscopic myomectomy on the sex hormone levels in patients with uterine leiomyoma
摘要
Abstract
Objective: To explore the effect of laparoscopic myomectomy on the sex hormone levels in patients with uterine leiomyoma (UL).Methods: A total of 102 patients with UL who were admitted in our hospital were included in the study and divided into the observation group and the control group with 51 cases in each group according to different surgical treatment protocols.The patients in the observation group were performed with laparoscopic myomectomy, while the patients in the control group were performed with laparoscopic total hysterectomy.The postoperative sex hormone, MAPK, p-ERK, and VEGF levels in the two groups were compared.Results: FSH and LH levels after operation in the two groups were significantly elevated when compared with before operation (P<0.05), while E2 and P levels were significantly reduced (P<0.05).FSH and LH levels after operation in the observation group were significantly higher than those in the control group (P<0.05), while E2 and P levels were significantly lower than those in the control group (P<0.05).The serum MAPK, p-ERK, and VEGF expression levels after operation in the two groups were significantly reduced when compared with before operation (P<0.05), while the comparison between the two groups was not statistically significant (P>0.05).Conclusions: Myomectomy has a small effect on the sex hormone levels in patients with UL, and should be preferred according to the condition.关键词
子宫肌瘤/子宫全切除术/子宫肌瘤剔除术/性激素Key words
UL/Total hysterectomy/Myomectomy/Sex hormone分类
医药卫生引用本文复制引用
叶凤霞..腹腔镜子宫肌瘤剔除术对子宫肌瘤患者性激素水平的影响[J].海南医学院学报,2017,23(7):932-934,3.基金项目
绵阳市卫生局科研课题(201331D) （201331D）
The study was supported by the Scientific and Research Project of Mianyang Health Bureau with the number of 201331D. （）
