河北医学2017，Vol.23Issue(3)：366-369,4.DOI:10.3969/j.issn.1006-6233.2017.03.005
2型糖尿病患者尿白蛋白排泄量与视网膜病变的相关性研究
Analysis on Relationship between Urinary Albumin Excretion with Diabetic Retinopathy in Type 2 Diabetics
摘要
Abstract
Objective:To analyze the relationship between urinary albumin excretion with diabetic retinopathy in type 2 diabetics.Methods:320 patients with type 2 diabetics were divided into normal albuminuria group(NA, n=68, 24h-urinary albumin≤30mg), microalbuminuria group(MAU, n=135, 30mg<24h-urinary albumin<300mg) and macroalbuminuria group(CAU,n=117,24h-urinary albumin≥300mg).All the patients were measured the 24h-urinary albumin and examined by digital retinal photographs, thus we can analyze the relationship between urinary albumin excretion with diabetic retinopathy in type 2 diabetics.Results:Simple retinopathy detection were 10.1%,42.9% and 43.3% in normal albuminuria group, microalbuminuria group and macroalbuminuria group, fertile retinopathy detection rate were 5.2%,15.8% and 35.4% in the 3 groups , statistically significant differences existed in the rate of simple retinopathy detection and fertile retinopathy detection of different groups(P<0.05).Correlation analysis results showed that there is positive correlation between urinary protein excretion and diabetic retinopathy in patients with type 2 diabetes(r=0.526, P<0.05).Conclusion:Urinary protein excretion were significantly correlated with the incidence of diabetic retinopathy in patients with type 2 diabetes, maybe they have common pathophysiological basis.关键词
2型糖尿病/尿白蛋白量/视网膜病变/相关性Key words
Type 2 diabetes/Urinary albumin excretion/Diabetic retinopathy/Correlate relationship引用本文复制引用
孙冠媛,王颖..2型糖尿病患者尿白蛋白排泄量与视网膜病变的相关性研究[J].河北医学,2017,23(3):366-369,4.基金项目
天津市科技计划项目,(编号:201321184) （编号:201321184）
