河北医学2017，Vol.23Issue(3)：408-411,4.DOI:10.3969/j.issn.1006-6233.2017.03.018
全麻老年患者术后静注氟马西尼影响认知功能和S100β蛋白的表达研究
Elderly Patients with General Anesthesia Postoperative Static Note Fluorine Marcie's Influence Cognitive Function and According to Research of Beta Protein Expression
摘要
Abstract
Objective:To study the anesthesia in elderly patients with postoperative static note fluorine marcie's influence cognitive function and according to beta protein expression.Methods:Chose between April 2015 and March 2016, orthopaedic surgery treated in our hospital 82 cases of elderly patients.According to random number table method was divided into observation group and the control group each had 41 cases.All patients with general anesthesia processing, then the control group was given 5 ml saline intravenous injection, the observation group were given fluorine marcie, 5 ml intravenous injection.Respectively compared two groups of patients bleeding amount of operating time, wake up of time, extubation time, MMSE score, serum according to beta protein levels before and after operation and the OAA/S score before and after injection.Results:The observation group of waking time, extubation time, respectively (8.7±3.1) min and (13.1±2.4) min, were significantly lower than in the control group (12.9±2.9) min and (15.8±3.7) min, differences were statistically significant (all P < 0.001).After 6 h, 1 d after operation, postoperative MMSE score 3 d observation group were significantly higher than that of control group, differences were statistically significant (all P < 0.001).6 h after surgery, postoperative serum according to beta level 1 d observation group were significantly lower than the control group, the difference had statistical significance (P < 0.05).1 min, 2 min, 5 min after injection of OAA/S score of observation group patients were significantly higher than the control group, the differences were statistically significant (all P < 0.05).Conclusion:General anesthesia in elderly patients with postoperative static note fluorine marcie, which can effectively shorten the postoperative patients with waking time, extubation time, at the same time improve patients MMES score, reduce according to beta protein concentration, reducing the occurrence of postoperative cognitive dysfunction in patients.关键词
氟马西尼/认知功能/S100β蛋白Key words
Fluorine marcie/Cognitive function/S100β protein引用本文复制引用
王婷,叶力肯·叶尔道来提,米日古丽,王龙..全麻老年患者术后静注氟马西尼影响认知功能和S100β蛋白的表达研究[J].河北医学,2017,23(3):408-411,4.基金项目
新疆维吾尔自治区自然科学基金,(编号:2014211C085) （编号:2014211C085）
