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2型糖尿病肾病患者血尿酸与炎症因子的相关性研究

何建秋 张蕊 孙志新 王英南 王丽红 刘畅 韩桂艳

河北医学2017,Vol.23Issue(3):430-433,4.
河北医学2017,Vol.23Issue(3):430-433,4.DOI:10.3969/j.issn.1006-6233.2017.03.025

2型糖尿病肾病患者血尿酸与炎症因子的相关性研究

Correlation Study of the Levels of Uric Acid With Inflammation Factor in Type 2 Diabetes

何建秋 1张蕊 1孙志新 1王英南 1王丽红 1刘畅 1韩桂艳1

作者信息

  • 1. 承德医学院附属医院,河北 承德 067000
  • 折叠

摘要

Abstract

Objective:To investigate the correlation of the levels of uric acid with inflammation factor in type 2 diabetes.Methods:One hundred and seven cases of patients with type 2 diabetes were divided into contral group, microalbuminuria group and clinical proteinuria group according to urinary albumin to creatinine ratio, the levels of uric acid and C-reactive protein were detected.Results:The levels of uric acid and C-reactive protein,TNF-α,ICAM-1 of contral group, microalbuminuria group and clinical proteinuria group were on the rise, the differences were statistically significant(P<0.05), the levels of uric acid with C-reactive protein,TNF-α,ICAM-1 were positively correlated.Conclusion:Uric acid leading to diabetic nephropathy through inflammatory reaction in type 2 diabetes.

关键词

糖尿病肾病/血尿酸/炎症因子

Key words

Diabetic nephropathy/Uric acid/Inflammation factor

引用本文复制引用

何建秋,张蕊,孙志新,王英南,王丽红,刘畅,韩桂艳..2型糖尿病肾病患者血尿酸与炎症因子的相关性研究[J].河北医学,2017,23(3):430-433,4.

基金项目

河北省承德市科学技术研究与发展计划项目,(编号:20132046) (编号:20132046)

河北医学

OACSTPCD

1006-6233

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