河北医学2017，Vol.23Issue(4)：529-532,4.DOI:10.3969/j.issn.1006-6233.2017.04.001
低剂量CT扫描及定量分析对慢性阻塞性肺疾病气道病变应用的初步研究
Preliminary Study on the Application of Low dose CT Scan and Quantitative Analysis in Patients with COPD
摘要
Abstract
Objective:To study the low dose CT scanning and quantitative analysis on the value of airway lesions in chronic obstructive pulmonary disease.Methods: From August 2015 to July 2016, selected 69 cases of COPD patients admitted in our hospital, according to the severity patients were divided into mild group of 26 cases, moderate group of 19 cases, severe group of 24 cases, and at the same time, choose the health check-up 30 cases as control group.All the research objects were received with low dose CT scanning and lung function test, and measured airway related parameters of the airway with quantitative CT analysis soft ware, and made spearman correlation analysis.Results: The contrast of FEV1, FEV1 / FVC of control group, mild group, moderate group and severe group showed a trend of gradual decline, the difference was statistically significance (P < 0.05).The contrast of WA/BSA, T/BSA, WA %, Pi10 of control group, mild group, moderate group and severe group showed a trend of rising, the difference had statistical significance (P < 0.05).FEV1 and WA %, a negative correlation relationship between Pi10 (r =-0.472, P =0.000;r =-0.484, P =0.000), FEV1 / FVC and WA %, were negatively correlated relationship between Pi10 (r =-0.501, P =0.000;r=-0.493, P =0.000).Conclusion: Low dose CT scanning and quantitative analysis can provide reliable assessment of COPD airway disease in patients with information, airway parameter WA %, Pi10 is an effective objective evaluation index.关键词
慢性阻塞性肺疾病/气道病变/CT扫描/定量分析Key words
Chronic obstructive pulmonary disease/Airway lesions/CT scan/Quantitative analysis引用本文复制引用
王永芹,段玉梅,宋丽华..低剂量CT扫描及定量分析对慢性阻塞性肺疾病气道病变应用的初步研究[J].河北医学,2017,23(4):529-532,4.基金项目
四川省科技厅科技支撑计划,(编号:2012SZ01574 （）
