中国实用神经疾病杂志2017，Vol.20Issue(8)：23-25,3.
小剂量替罗非班与双抗治疗进展性脑卒中的疗效对比及安全性评价
Comparison between small dose of tirofiban and aspirin combined with clopidogrel in the treatment of progressive stroke in terms of efficacy and safety
王升 1刘梦 1郑远征 1方敬献1
作者信息
- 1. 河南南阳市第一人民医院神经内一科 南阳 473000
- 折叠
摘要
Abstract
Objective To compare the clinical efficacy between tirofiban and aspirin combined with clopidogrel in treatment of progressive stroke and to evaluate their safety.Methods We selected 60 patients with acute stroke from July 2015 to October 2016,whose condition developed into progressive stroke within one week and neurological deficit scores were aggravated.28 cases who initially received small dose of tirofiban and later received aspirin combined with clopidogrel were selected as study group,while other 32 cases merely treated with aspirin plus clopidogrel were selected as control group.Three and seven days after treatment,NIHSS scores,BI index,platelet count,coagulation indicators,bleeding and other complications were compared between two groups.Results Three days after treatment,the NIHSS scores of two groups showed significant difference(P<0.05),while BI index showed no difference(P>0.05).Seven days after treatment,both NIHSS scores and BI index between two groups were significantly different(P<0.05).Conclusion Small dose of triofiban has a promising effect on treating progressive stroke with good security,which can improve patients' prognosis.关键词
替罗非班/进展性脑卒中/阿司匹林/氯吡格雷Key words
Tirofiban/Progressive stroke/Aspirin/Clopidogrel分类
医药卫生引用本文复制引用
王升,刘梦,郑远征,方敬献..小剂量替罗非班与双抗治疗进展性脑卒中的疗效对比及安全性评价[J].中国实用神经疾病杂志,2017,20(8):23-25,3.
