解放军医学院学报2017，Vol.38Issue(4)：309-312,4.DOI:10.3969/j.issn.2095-5227.2017.04.005
55例局部中晚期直肠癌术前调强放疗摆位误差及影响因素分析
Set-up errors of preoperative intensity-modulated radiotherapy for locally advanced rectal cancer and their impact factors: Analysis of 55 patients
摘要
Abstract
Objective To analyze the set-up errors of preoperative intensity modulated radiation therapy (IMRT) in locally advanced rectal cancer and its impact factors, and provide important evidence to improve geometric accuracy and radiotherapy precision. Methods Fifty-five patients with locally advanced rectal cancer treated with preoperative IMRT in Chinese PLA General Hospital from 2014 to 2016 were enrolled. All CBCT images were obtained using on-board imaging system on a Varian Clinac iX linear accelerator. Automatic image registration of the CBCT to the planning CT was performed, and the set-up parameters including left/right (X), superior/inferior (Y), anterior/posterior (Z) directions and rotation (Roll) about X axis were recorded and corrected before radiotherapy implementation. Results All cases had undergone 869 CBCT scans. The average setup errors in the X, Y, Z axes and Roll were(1.50±1.95)mm, (3.05±5.09) mm, (1.42±1.88) mm and (0.8±0.10)°, respectively. The corresponding CTV-to-PTV margins in the direction of X, Y, and Z axes were 5.12 mm, 11.2 mm, 4.87 mm. There were no significant differences between the first 5 and the last 5 set-up and rotation errors (P > 0. 05). Univariate analysis showed that the setup errors of X, Y, Z directions were no significant differences in age, gender, body mass index, tumor distance from anus and tumor which received simultaneous integrated boost (SIB). Conclusion The set-up errors are greater in Y direction than those in X and Z axes during preoperative IMRT of rectal cancer in the supine position and the rotation errors are much smaller and can be omitted.关键词
直肠癌/术前放疗/摆位误差/调强放疗Key words
rectal cancer/preoperative radiotherapy/set-up errors/intensity modulated radiation therapy分类
医药卫生引用本文复制引用
刘其腾,王运来,郑庆增,杨涛,曾铭玥,巩汉顺,黄海棠,冯林春..55例局部中晚期直肠癌术前调强放疗摆位误差及影响因素分析[J].解放军医学院学报,2017,38(4):309-312,4.基金项目
科技部国家重点研发计划(2016YFC0105712) Supported by Research and Development Program of Ministry of Science and Technology of China (2016YFC0105712) （2016YFC0105712）
