解放军医学院学报2017,Vol.38Issue(4):345-348,4.DOI:10.3969/j.issn.2095-5227.2017.04.014
系统性红斑狼疮并发新型隐球菌脑膜炎1例报道
Concurrent cryptococcal meningitis and systemic lupus erythematosus : A case report
陈盼 1孙飞 2朱剑 2张江林2
作者信息
- 1. 荆州市中心医院 风湿科,湖北荆州 434020
- 2. 解放军总医院 风湿科,北京 100853
- 折叠
摘要
Abstract
Objective To improve the understanding of systemic lupus erythemmatosus (SLE) associated with cryptococcal meningitis (CM) through a case report and literature review. Methods Clinical data of one case of SLE patient with CM was reported, followed by review of relevant literatures, to summarize the characteristics of this disease. Results This patient was a 33-year-old female, receiving long-term of hormone and immunosuppressive therapy for SLE. During the disease course, the patient had a sudden onset of epilepsy, which was confirmed to be CM due to the cryptococcus neofonmans in the cerebrospinal fluid smear and culture. Conclusion SLE accompanied with CM is a rare disease. When epilepsy occurs in the SLE patients, besides active SLE, the possibility of central nervous system infection should be considered. Timely and effective lumbar puncture, cerebrospinal fluid smear and culture are important to confirm this disease.关键词
系统性红斑狼疮/新型隐球菌/新型隐球菌脑膜炎Key words
systemic lupus erythemmatosus/cryptococcus neoformans/crytococcus neofonmans meningtis分类
医药卫生引用本文复制引用
陈盼,孙飞,朱剑,张江林..系统性红斑狼疮并发新型隐球菌脑膜炎1例报道[J].解放军医学院学报,2017,38(4):345-348,4.