摘要
Abstract
Objective To study the diagnostic value of human neutrophil lipocalin(HNL),procalcitonin(PCT) and CRP in acute bacterial infection.Methods Three hundreds and fifty inpatients with acute infectious diseases in the hospital from June 2015 to December 2015 were selected,including 184 cases of bacterial infection(bacterial group) and 166 cases of viral infection(viral group).Contemporaneous 155 staffs receiving the healthy physical examination or enrolled students were chosen as the control group.Serum HNL,PCT and CRP values in all subjects were detected by using ELISA,double antibody sandwich chromatography and immunoturbidimetry.Results The levels of PCT,HNL and CRP in the bacterial group were (2.41±1.23)ng/mL,(232.54±101.23)ng/mL and (55.14±38.47)mg/L respectively,which were significantly higher than those in the viral group and the control group,moreover the increase of detected HCL level was most obvious,the difference was statistically significant(P<0.05).At the same time the positive rates of PCT,HNL and CRP in the bacterial infection group were 82.06%,94.02% and 70.65% respectively,which were far out of those in the viral group and control group,the difference was statistically significant(P<0.05),but the difference between the latter two groups had no statistical difference(P>0.05).Conclusion HNL,PCT and CRP are more sensitive to bacterial infection,which have a strong differential diagnosis capacity,in which the NHL increase is most significant with strong specificity and high accuracy,and can provide an important reference basis for the early diagnosis.关键词
中性粒细胞载脂蛋白/降钙素原/C反应蛋白/急性细菌感染/诊断价值Key words
human neutrophil lipocalin/procalcitonin/C-reactive protein/acute bacterial infection/diagnostic value
