临床误诊误治2017，Vol.30Issue(4)：31-35,5.DOI:10.3969/j.issn.1002-3429.2017.04.011
伴肝功能异常的成人Still病误诊三例报告并文献复习
A Case Report and Literature Review of 3 Misdiagnosed Patients with Adult-onset Still's Disease Associated by Abnormal Liver Function
摘要
Abstract
Objective To investigate clinically atypical manifestations of adult-onset Still's disease (AOSD) to decrease misdiagnosis and mistreatment.Methods Clinical data of 3 patients with AOSD associated by abnormal liver function was retrospectively analyzed, and related literature was reviewed.Results All the 3 patients visited doctors for fever of undetermined origin and abnormal liver function, and were misdiagnosed as having drug-induced liver injury and (or) acute hepatitis and (or) liver abscess, but the patients' conditions did not improve after using lots of antibiotics and hepatic protectant medicines.After being transferred to our hospital, AOSD was confirmed according to clinical symptoms and medical examination results.Patients' conditions turned better after glucocorticoid treatment.All patients had no fever again with normal liver function during follow-up.Conclusion The abnormal liver function can be one of the features of part of the ASOD patients.Clinicians should consider possibility of AOSD for patients with the clinical manifestations of fever, joint pain, rash, sore throat, liver spleen lymphadenovarix, increased blood leukocytes, neutrophil granulocytes and ferroprotein and abnormal liver function have no effect after lots of antibiotics treatment, and the possibilities of infection, tumour or rheumatic immunologic diseases are excluded.关键词
Still病/成年型/原因不明发热/误诊/药物性肝损伤/肝炎/肝脓肿Key words
Still disease/adult-onset/Fever of unknown origin/Misdiagnosis/Drug-induced liver injury/Hepatitis/Liver abscess分类
医药卫生引用本文复制引用
赵嵩琪,钱远宇,孟庆义..伴肝功能异常的成人Still病误诊三例报告并文献复习[J].临床误诊误治,2017,30(4):31-35,5.
