临床误诊误治2017，Vol.30Issue(4)：52-54,3.DOI:10.3969/j.issn.1002-3429.2017.04.018
误诊为遗传性球形红细胞增多症的自身免疫性溶血性贫血
A Case Report of Autoimmune Hemolytic Anemia Misdiagnosed as Hereditary Spherocytosis
解飞 1洪萍 1周霖 1蔡斌 1雷蕾 1陈若华1
作者信息
- 1. 00433 上海,第二军医大学附属长海医院儿科
- 折叠
摘要
Abstract
Objective To investigate clinical characteristics, misdiagnosed causes and preventive measures of autoimmune hemolytic anemia (AIHA).Methods Clinical data of one AIHA patient misdiagnosed as having hereditary spherocytosis was retrospectively analyzed.Results A 8-years-old patient was admitted for ochrodermia, tea-colored urine for 2 months and aggravation for 1 month.He was misdiagnosed as having hereditary spherocytosis after examinations such as red blood cell morphology examination, Coomb's test and hemolysis test in other hospital, and was discharged after treatment of blood transfusion, and was going to undergo splenectomy.AIHA was confirmed after positive results of rechecking Coomb's test by indirect and direct methods combined with hemolytic anemia in our hospital.The patient was treated with blood transfusion, immunoglobulin supplement and immunosuppression, and was discharged after having normal hemoglobin level.Conclusion Both AIHA and hereditary spherocytosis show hemolytic anemia, and differential diagnosis is mainly based on Coomb's test, but negative result of one time Coomb's test can not exclude AIHA, and therefore clinicians should give Coomb's test for many times for suspected children, and related gene test of heritage erythrocyte membrane diseases can be performed to accurately diagnose and treat if the condition is permissibility.关键词
贫血/溶血性/自身免疫性/儿童/误诊/球形红细胞增多/遗传性Key words
Anemia/hemolytic/autoimmune/Child/Misdiagnosis/Spherocytosis/hereditary分类
医药卫生引用本文复制引用
解飞,洪萍,周霖,蔡斌,雷蕾,陈若华..误诊为遗传性球形红细胞增多症的自身免疫性溶血性贫血[J].临床误诊误治,2017,30(4):52-54,3.
