临床与实验病理学杂志2017，Vol.33Issue(2)：161-164,4.DOI:10.13315/j.cnki.cjcep.2017.02.010
口腔颌面部成人型横纹肌瘤3例临床病理分析
Adult rhabdomyoma in the oral and maxillofacial region: a clinicopathologic study of three cases
摘要
Abstract
Purpose To investigate the clinicopathological features of the adult rhabdomyoma (A-RM) in the oral and maxillofacial region.Methods Three cases of A-RM in the oral and maxillofacial region were analyzed for the clinical symptoms,imaging data,pathological features,differential diagnosis,treatment,and prognosis with the literatures review.Results The age arranged from 4 yea~ to 83 years in three A-RM cases.Two cases were male and one case was female.Two cases occurred in the mouth floor and one case in the tongue.Three A-RM cases presented as slowly growing,painless masses clinically.The masses were lobular,red-brown nodules with clear boundary.Histologically,they consisted of densely packed,large,round and polygonal cells with abundant granular eosinophilic cytoplasm.Cross striations and vacuoles were seen in the cytoplasm.Tumor cells expressed desmin and myoglobin,partially expressed SMA,MyoD1 and S-100 protein.PAS was also positive among tumor cells and could be digested by the diastasum diastace.Conclusion Histological examination is the main diagnostic basis for A-RM.For accurate diagnosis,cross striations and immunohistochemistry for myogenic proteins in cytoplasm are of pivotal importance.Radical resection is the main treatment with generally promising prognosis.关键词
软组织肿瘤/成人型/横纹肌瘤/病理学特征/免疫组织化学Key words
soft tissue neoplasms/adult rhabdomyoma/clinicopathological features/immunohistochemistry分类
医药卫生引用本文复制引用
张磊,杨艳,陈盛,周婷,王毓佳,黄晓峰..口腔颌面部成人型横纹肌瘤3例临床病理分析[J].临床与实验病理学杂志,2017,33(2):161-164,4.基金项目
江苏省卫生厅面上科研课题(H201344)、江苏省卫计委住院医师规范化培训课题(C2016033) （H201344）
