临床与实验病理学杂志2017，Vol.33Issue(2)：174-177,4.DOI:10.13315/j.cnki.cjcep.2017.02.013
涎腺肌上皮癌12例临床病理分析
Clinicopathological study of 12 cases of salivary myoepithelial carcinoma
曹培龙 1张少强 2赵继元 2闫金凤 2姚小宝 2张鹏飞 2刘利锋2
作者信息
- 1. 西安交通大学第一附属医院病理科,西安710061
- 2. 西安交通大学第一附属医院耳鼻咽喉头颈外科,西安710061
- 折叠
摘要
Abstract
Purpose To study the clinical features,pathological manifestation and immunohistochemical phenotype and improve the diagnosis and treatment of myoepithelial carcinoma in salivary glands.Methods Histomorphology and immunohistochemical phenotype were analyzed after the sections were stained with routine HE and immunohistochemical methods,and the relevant literatures were reviewed.Results The tumours were predominantly composed of pale-stained clear cells.In some cases,plasma-like cells,epithelioid cells and spindle cells were also seen.The cells were arranged in nest,solid or cords.Mitosis was easily seen,cytological atypia was obvious and necrosis existed in 4 cases.The results of immunohistochemical staining showed that CK was expressed in all cases.EMA was expressed in 8 cases.p63 and CK5/6 were expressed in 11 cases.S-100 was expressed in 10 cases.vimentin was expressed in 4 cases.Calponin was expressed in 2 cases.SMA was expressed in one case.The proliferation index of Ki-67 was 5％ to 40％.Conclusion The histological changes of myoepithelial carcinoma cells are diverse,and pathological and immunohistochemical methods are helpful for improving the rate of right diagnosis.Sugery is the main treatment for myoepithelial carcinoma.关键词
涎腺肿瘤/肌上皮癌/涎腺/免疫组织化学Key words
salivary gland neoplasms/myoepithelial carcinoma/salivary gland/immunohistochemistry分类
医药卫生引用本文复制引用
曹培龙,张少强,赵继元,闫金凤,姚小宝,张鹏飞,刘利锋..涎腺肌上皮癌12例临床病理分析[J].临床与实验病理学杂志,2017,33(2):174-177,4.
