国际眼科杂志2017，Vol.17Issue(5)：937-940,4.DOI:10.3980/j.issn.1672-5123.2017.5.34
飞秒激光小切口基质透镜取出术治疗近视及散光
Clinical study of small incision lenticule extraction for the correction of myopia and astigmatism
摘要
Abstract
AIM:To investigate the clinical safety,efficacy,predictability and stability of small incision lenticule extraction (SMILE) for the correction of myopia and astigmatism.METHODS:This was a prospective clinical controlled study involved 547 patients (1080 eyes) with myopia and astigmatism.Out of these,560 eyes of 285 patients were treated with SMILE and 520 eyes of 262 patients were treated with femtosecond laser assisted laser in situ keratomileusis (FS-LASIK).The patients were followed up 12mo after operation and received ophthalmologic examinations including uncorrected visual acuity(UCVA),best corrected visual acuity(BCVA),manifest refraction,slitlamp examination and corneal topography at 1d,1wk and 1,6 and 12mo.The value of decentration from pupil center was measured at 3mo.RESULTS:The UCVA at 1d,1wk,1,6 and 12mo were respectively 0.029±0.13 LogMAR,0.001±0.11LogMAR,-0.019±0.11 LogMAR,-0.020±0.08 LogMAR,-0.011±0.10 LogMAR in SMILE group,and-0.017±0.08 LogMAR,-0.019±0.09 LogMAR,-0.031±0.10 LogMAR,-0.024±0.09 LogMAR,-0.002±0.12 LogMAR in FS-LASIK group.The UCVA in SMILE group were significantly lower than that in FS-LASIK group at 1d and 1wk(P<0.05),while no difference were observed at other time points.The spherical equivalent(SE) at 1,6 and 12mo were respectively-0.03±0.29D,-0.04±0.28D,-0.06±0.32D in SMILE group,and 0.02±0.20D,-0.01±0.29D,-0.08±0.33D in FS-LASIK group,and the difference was statistically significant at 1mo(P<0.05),except other time points.At 3mo,the mean decentration from pupil center were 0.21±0.11mm for SMILE group and 0.20±0.08mm for FS-LASIK group,there was no significant difference between the two groups(P>0.05).CONCLUSION:SMILE is effective,predictable,stable and safe for myopia and astigmatism.However,SMILE showed slower vision recovery compared with FS-LASIK in the early postoperative period.关键词
近视/散光/飞秒激光/小切口基质透镜取出术Key words
myopia/astigmatism/femtosecond laser/small incision lenticule extraction引用本文复制引用
马代金,张青松,蔡望,朱睿玲..飞秒激光小切口基质透镜取出术治疗近视及散光[J].国际眼科杂志,2017,17(5):937-940,4.基金项目
湖南省卫生计生委科研基金(No.B2015-143) （No.B2015-143）
爱尔眼科医院集团科研基金(No.AM149D18) （No.AM149D18）
Health and Family Planning Commission Research Fund of Hunan Province,China (No.B2015-143) （No.B2015-143）
Aier Eye Hospital Group Research Fund (No.AM149D18) （No.AM149D18）
