焦风 1张磊 2赵春维 1刘波 1王栋梁 1梁冶矢 1刘献增1
作者信息
- 1. 北京大学人民医院,北京100044
- 2. 乌鲁木齐市友谊医院
- 折叠
摘要
Abstract
Objective To investigate the prognostic value of intraoperative lateral spread response (LSR) monitoring in the treatment of hemifacial spasm (HFS) by microvascular decompression (MVD). Methods Forty-five patients with primary HFS treated by MVD. During operations, we performed LSR monitoring before and after MVD respectively. All patients were assessed after operation on day 1 and 7, and at 3 month after surgery by self-assessment scale. We analyzed the relationship between the change of LSR and prognosis. Results In 40 patients, the LSR disappeared immediately after decompression (LSR disappeared group). In the remaining 5 patients, the LSR did not vanish immediately after decompression (LSR non vanishing group), one patient's LSR decreased 86％, 2 patients' LSR decreased above 50％, 1 patient had no change, and in 1 patient, LSR was not detected from the start. On day 1 after operation, in the LSR disappeared group, HFS was relieved totally in 31 patients, 9 patients described improvement; in the LSR non vanishing group, 1 patient totally relieved, 1 patient improved, and 3 patients failed. On day 7, in the LSR disappeared group, HFS was relieved totally in 35 patients, 5 patients described improvement; in the LSR non vanishing group, 1 patient totally relieved, 2 patient improved, and 2 patients failed. After 3 month, in the LSR disappeared group, HFS was relieved totally in 39 patients, 1 patients described improvement; in the LSR non vanishing group, 3 patient improved, and 2 patients failed. After 3-month to 88-month follow-up, in the LSR disappeared group, all the 40 patients cured, in the LSR non vanishing group, 3 patients improved and 2 patients failed. At all the postoperative observing time, the proportion of cure and improvement of the LSR disappeared group was higher than that of the LSR non vanishing group. Statistical analysis found a significant correlation between the relief of LSR and clinical outcome (all P<0.05). Conclusion LSR monitoring of HFS patients in MVD is correlated with the curative effect, and the rate of cure and improvement is higher in patients with disappeared LSR after decompression.关键词
面肌痉挛/微血管减压术/侧方扩散反应Key words
hemifacial spasm/microvascular decompression/lateral spread response分类
医药卫生
