世界中医药2017，Vol.12Issue(4)：803-806,4.DOI:10.3969/j.issn.1673-7202.2017.04.024
中药外敷法对轻中度膝关节骨性关节炎WOMAC评分和VAS评分的影响
Effect of External Application of Chinese Medicinal on Mild-to-moderate Osteoarthritis of Knee WOMAC and VAS Scores
摘要
Abstract
Objective:To evaluate the therapy efficacy and safety of external application of Chinese medicinal in treatment of mild-to-moderate knee joint osteoarthritis by the WOMAC and VAS scores.Methods:A total of 72 mild-to-moderate knee joint osteoarthritis patients were selected and randomly divided to two groups:external application of Chinese medicinal group(n=36) and the western medicine group(n=36).External application of Chinese medicinal group was given external application of Chinese medicinal on their ashi point, 48 hours each time, the medicinal was changed every 2 or 3 days, twice per week;the western medicine group patients took glucosamine sulfate capsules orally every day, two pieces each time and three times each day.The two groups were treated for four weeks.The WOMAIC and the VAS scores were used to evaluate the efficacy before treatment, 2 weeks after treatment and 1 month after treatment.The VAS pain score was used to assess efficacy of 3 months after treatment as the long-term outcome.Results:During the treatment, 2 cases fell off in external application of Chinese medicinal group.No one fell off in oral drug group.There were significant differences (P<0.05) in VAS pain score in both groups compared with the statistics before the treatment, 2 weeks, 1 months and 3 months after the treatment.There were also significant differences (P<0.05) in WOMAC scores in both two groups compared with the statistics before the treatment, 2 weeks and 1 month after treatment.There were significant differences in VAS pain score (P<0.05) after two weeks' treatment between the two groups, but no differences in WOMAC scores.No significant differences were shown in VAS pain score and WOMAC scores after 1 month's treatment in two groups.One case in external application Chinese medicinal group showed mild allergy (adverse effect rates=3%).Three cases experienced gastrointestinal tract reaction in western medicine (adverse effect rates=8%).Conclusion:External application of Chinese medicinal is a safe and effective treatment with certain long-term effect.关键词
中药外敷/膝关节骨性关节炎/WOMAC评分/VAS评分Key words
External application of Chinese medicinal/Knee osteoarthritis/WOMAIC score/VAS pain score分类
医药卫生引用本文复制引用
李华,方志远,柏立群,李运海,徐愿,胡慧..中药外敷法对轻中度膝关节骨性关节炎WOMAC评分和VAS评分的影响[J].世界中医药,2017,12(4):803-806,4.基金项目
北京中医药大学青年教师专项计划课题(编号:2013-JYBZZ-JS-17901) （编号:2013-JYBZZ-JS-17901）
北京市中医药管理局:中医药"3+3"薪火传承《杨甲三名家研究室》课题 （）
国家自然科学基金青年项目(编号:81603588) （编号:81603588）
