兽类学报2017，Vol.37Issue(2)：162-171,10.DOI:10.16829/j.slxb.201702007
暖温经历对雌性黑线仓鼠能量代谢、产热和体脂含量的影响
The effects of warm temperature on energy metabolism, thermogenesis and body fat content in female striped hamsters
摘要
Abstract
Proper adjustment of energy metabolism is one of the most important strategies in small mammals in response to variations in ambient temperature.The present study was designed to test the roles and mechanisms of metabolic thermogenesis in the adaptive regulation of body mass and body fat under warm temperatures.Body mass,energy intake,metabolic thermogenesis were determined in striped hamsters that were acclimated to warm temperature (30℃) for 1,3 and 4months.Cytochrome c oxydase (COX) activity and mRNA expression of uncoupling protein 1 (UCP1) in brown adipose tissue (BAT) were also measured.The results showed that warm temperature had no effect on body mass,but significantly increased body fat.Digestibility increased significantly in warm-acclimated hamsters compared to those maintained at 21℃,but the gross and digestive energy intake were significantly reduced.Nonshivering thermogenesis (NST) was reduced significantly under warm temperature.COX activity in brain,liver and heart was significantly reduced,and BAT COX activity and UCP1 mRNA expression significantly were decreased in warm-exposed hamsters compared to those maintained at 21 ℃.These findings suggest that the decrease in the energy expended for metabolism and thermogenesis compensates for the decreased energy intake,resulting in a positive energy balance,and consequently contributes to the increase in fat deposition.Down-regulation of metabolic rate of brain,liver,heart and BAT is the physiological mechanism underpinning the reduction of metabolic thermogenesis,which may be involved in the fat deposition in response to warm temperature.关键词
暖温/产热/体脂含量/黑线仓鼠Key words
Body fat content/Striped hamsters/Thermogenesis/Warm temperature分类
生物科学引用本文复制引用
谭松,闻靖,赵志军..暖温经历对雌性黑线仓鼠能量代谢、产热和体脂含量的影响[J].兽类学报,2017,37(2):162-171,10.基金项目
国家自然科学基金资助项目(31270458) （31270458）
