生物骨科材料与临床研究2017，Vol.14Issue(2)：5-10,后插1,7.DOI:10.3969/j.issn.1672-5972.2017.02.002
仿生人工腰椎及椎间盘复合体的设计及活动度分析
Design and activity analysis of bionic artificial lumbar vertebra and disc complex
摘要
Abstract
Objective To design a type of bionic movable prosthesis which can reconstruct the height of lumbar vertebra and preserve the motion of inter-vertebral discs after lumbar subtotal corpectomy for the treatment of the tumor,tuberculosis and fracture of lumbar vertebra.Methods To extract the lumbar CT scan data of 60 healthy male adults of our country for three dimensional reconstruction using Mimics 16.0 and measure the anatomic parameters of lumbar vertebra and inter-vertebral disc.To statistically analyze the anatomic data using IBM SPSS statistics 21 and design three dimensional model of bionic artificial lumbar vertebra and disc complex with Solidworks 2013 according the statistical parameters.Then we create a photosensitive resin model of the movable prosthesis with 3D-printing technology and make a preliminaryassessmentofitsactivity.Results Comparing to anterior and posterior vertebral body height,the middle height of vertebra is smaller.The median saggital and crown diameters of superior and inferior endplates are bigger than those of middle horizontal plane.The angle of upper and lower endplates with profile of lumbar vertebra is about more than 70° and there's no difference among different vertebra (P＞0.05).However,thesagdepthofsuperiorandinferiorendplates exist significant difference (P＜0.05).The thickness of inter-vertebral disc obeys the law:anterior height＞middle height＞ posterior height and there is significant difference between anterior and posterior height (P＜0.05).Bionic artificial lumbar vertebra and disc complex is composed of three parts:vertebral body parts,inter-vertebral disc parts and screws.The materials of the prosthesis are medical titanium alloys and polymer materials.Its mobile device is anti-extrusion ball-socketjoint meeting axial rotation 360°,left or right sidebend 10°andflexionorextension15.Conclusion Three-dimensional CT reconstruction can accurately measure anatomic parameters of the lumbar spine.Bionic artificial lumbar vertebra and disc complex can meet lumbar physiological functions to a certain extent,but there is still deficiency of excessive axial rotation and its stability,biocompatibility,corrosion resistance,wear resistance and so on need further study.关键词
人工椎体/腰椎/脊柱肿瘤/脊柱结核Key words
Artificial vertebral body/Lumbar vertebra/Spinal tumor/Spinal tuberculosis分类
医药卫生引用本文复制引用
刘俭涛,李浩鹏,牛斌斌,李宇欢,高正超,贺西京..仿生人工腰椎及椎间盘复合体的设计及活动度分析[J].生物骨科材料与临床研究,2017,14(2):5-10,后插1,7.基金项目
高等学校博士博士学科点专项科研基金(20120201130009) （20120201130009）
