实用肝脏病杂志2017，Vol.20Issue(3)：381-384,4.DOI:10.3969/j.issn.1672-5069.2017.03.037
肝纤维化进程中细胞外基质对肝星状细胞的作用及机制研究进展
Influence of extracellular matrix on hepatic stellate cells during liver fibrosis process
摘要
Abstract
Liver fibrosis is a pathological process characterized by intrahepatic diffuse excess deposition of extracel ular matrix (ECM),and hepatic stellate cells (HSC) activation. This article mainly reviewed the changes of various components of ECM,the molecular structure and the spatial structure of the ECM in the process of hepatic fibrosis. And we also summarized the mechanism by which the effects of these changes on the activation,proliferation and apoptosis of HSCs.关键词
肝纤维化/细胞外基质/肝星状细胞Key words
Liver fibrosis/Extracel ular matrix/Hepatic stellate cell引用本文复制引用
秦雨萌,陈胜华..肝纤维化进程中细胞外基质对肝星状细胞的作用及机制研究进展[J].实用肝脏病杂志,2017,20(3):381-384,4.基金项目
南华大学"蒸湘学者"计划资助项目(编号:2016ZXXZ006) （编号:2016ZXXZ006）
湖南省研究生创新课题(编号:CX2016B476) （编号:CX2016B476）
