实用医学杂志2017，Vol.33Issue(5)：722-724,3.DOI:10.3969/j.issn.1006⁃5725.2017.05.012
慢性肾衰竭患者血液透析前后眼内压与房角结构的变化
Changes in the intraocular pressure and anterior chamber angle in patients with chronic renal failure before and after hemodialysis
摘要
Abstract
Objective To investigate changes in the intraocular pressure(IOP) and anterior chamber angle in patients with chronic renal failure before and after hemodialysis. Methods Fifty?eight patients(116 eyes) with chronic renal failure were measured with Goldmann applanation tonometer and anterior segment optical coherence tomograph. The patients were divided into three groups based on gonioscopy results:the narrow angle group(22 eyes),the Iris neovascular group(3 eyes)and the open angle group(91 eyes). IOP was measured by Goldmann applanation tonometer in patients in the three groups before and after hemodialysis. Anterior chamber angle opening distance (AOD) was detected by anterior segment optical coherence tomograph before and after hemodialysis. The blood urea nitrogen,creatinine,albumin were also determined before and after hemodialysis. All changes in the parameters were analyzed with a paired t test. Results The IOP in narrow angle eyes and in neovascular eyes increased significantly after hemodialysis ,while the IOP in open angle eyes showed no significant changes. The AOD decreased significantly after hemodialysis. The blood urea nitrogen and creatinine decreased significantly in 58 patients,while albumin increased after hemodialysis. Conclusion The IOP in narrow angle eyes and in neovascular eyes increased after hemodialysis ,correlating with the resistance increase of aqueous outflow pathway and the change of plasma osmotic pressure. As a result ,it is recommended that the condition of eye of patients with chronic renal failure should be checked ,and patients should receive appropriate controlling measure or treatment before hemodialysis.关键词
慢性肾衰竭/血液透析/眼内压/房角开放距离Key words
Chronic renal failure/Hemodialysis/Intraocular pressure/Angle opening distance引用本文复制引用
郑海生,钟兴武,陈海波,邢健强,史贻玉..慢性肾衰竭患者血液透析前后眼内压与房角结构的变化[J].实用医学杂志,2017,33(5):722-724,3.基金项目
海南省自然科学基金项目(编号:20158358) （编号:20158358）
