眼科新进展2017，Vol.37Issue(4)：348-350,3.DOI:10.13389/j.cnki.rao.2017.0088
多胎与单胎早产儿视网膜病变的发病率及危险因素的比较
Incidence and risk factors of retinopathy of prematurity among the multiple and single gestation births
摘要
Abstract
Objective To analyze the incidence and the risk factors of retinopathy of prematurity (ROP) among the multiple and single gestations births.Methods A prospective control study was applied to the research.The preterm infants were selected that from September 2013 to December 2015 in neonatology department of our hospital.They were divided into multiple gestations group (52 cases) and single birth infants group (600 cases).RetCam Ⅲl retina camera and binocular indirect ophthalmoscope video were used to screening the ocular fundus.The cure rate of the two groups was compared with chi-square test.Results The incidence of ROP in multiple gestations group (32.69％) was higher than single birth infants group (20.83％) (P =0.047).There was significant difference about the multiple and single gestations births in ≤ 30 weeks (P =0.040),and there was no statistically significant difference in ＞ 30 weeks (all P ＞0.05).With the increase of birth weight,the ROP detection rate of two groupa was reduced.There was no statistically significant difference about different birth weight among the two groups (all P ＞ 0.05).The oxygen usage of ＞ 5 days ROP detection rate was higher than 5 days or less in the two groups (P =0.025,0.001).There was no significant difference in ROP detection rate between two groups with ≤5 d oxygen usage.There was significant difference about the multiple and single gestations births in oxygen usage of ＞ 5 days (P =0.020).Multivariate analysis found that multiple gestations and small gestational age were risk factors for ROP.Conclusion The smaller gestational age,the lower birth weight,and the longer oxygen therapy with the preterm infants,the higher the incidence of ROP.The number of different gestational is also the influences factors of ROP.Multiple gestations overall incidence of ROP is higher than the single birth infants.The smaller the gestational age and the longer oxygen usage,multiple gestations incidence of ROP is higher than single gestation in different births.However,there is no relationship in different birth weight among the multiple and single gestations.关键词
视网膜病变/早产儿/多胎妊娠/出生低体质量/吸氧Key words
retinal diseases/preterm infants/multiple gestations/low birth weight/oxygen inhalation therapy分类
医药卫生引用本文复制引用
郭佃强,韩梅,单若冰,刘冰..多胎与单胎早产儿视网膜病变的发病率及危险因素的比较[J].眼科新进展,2017,37(4):348-350,3.基金项目
山东省医药卫生科技发展计划项目(编号:2016WS0298) （编号:2016WS0298）
青岛市医药科研指导计划(编号:2015-WJZD082)Projects of Medical and Health Technology Development Program in Shandong Province (No:2016WS0298) （编号:2015-WJZD082）
Medical and Scientific Research Guide Plan of Qingdao(No:2015-WJZD082) （No:2015-WJZD082）
