眼科新进展2017，Vol.37Issue(4)：379-383,5.DOI:10.13389/j.cnki.rao.2017.0097
干性年龄相关性黄斑变性治疗的研究进展
Research advances in therapy of dry age-related macular degeneration
摘要
Abstract
Age-related macular degeneration(AMD) is the major cause of irreversible damage to vision in over 60 years old.Its incidence is increasing with age.Dry AMD is one of the most common types,causing the loss of vision is very slow.At the late stage,the geographic atrophy will be found,in which central vision is severely lost.It is widely believed that chronic inflammantion injury,oxidative stress injury,lipofuscin,drusen and choroid ischemia are the major pathogenesis.Now,the treatment is major aiming to the pathogenesis.But some new therapies such as crocetin,curcumin,ciliary neurotrophic factor,nanoceria,human monoclonal antibody,photoreceptor and stem cell transplantation have some efficiency to dry AMD.This article reviews the research advances in therapy of dry AMD.关键词
干性年龄相关性黄斑变性/氧化应激/脂褐质/玻璃膜疣/睫状神经营养因子/纳米二氧化铈/人单克隆抗体/光感受器移植Key words
dry age-related macular degeneration/oxidative stress/lipofuscin/drusen/ciliary neurotrophic factor/nanoceria/human monoclonal antibody/photoreceptor transplantation分类
医药卫生引用本文复制引用
张燕枝,彭惠..干性年龄相关性黄斑变性治疗的研究进展[J].眼科新进展,2017,37(4):379-383,5.基金项目
国家自然科学基金资助(编号:81670881)National Natural Science Foundation of China (No:81670881) （编号:81670881）
