湖北医药学院学报2016，Vol.35Issue(4)：391-393,3.DOI:10.13819/j.issn.1006-9674.2016.04.014
11～13+6周胎儿超声筛查在产前诊断中的临床价值
Clinical Signifiance of Ultrasonography on Prenatal Diagnosis at 11 ～ 13+6 Gestational Age
摘要
Abstract
Objective To establish the normal reference values of the thickeness of nuchal translucency(NT) and exlpore the clinical significance of ultrasonography on screening fetal abnormality at 11 ～ 13+6 gestational age.Methods Total 1 918 fetuses with the crown rump length(CRL) from 45 to 84 mm were underwent ultrasound examination at 11 ～ 13+6 gestational age.The thicknesses of CRL and NT were measured according to guidelines of Fetal Medicine Foundation(FMF).The 5th,25th,50th,75th and 95th percentiles of the NT thickness values were analyzed within each 5 mm range of CRL.The pregnancy outcomes of cases with fetal structure abnormal development were followed up.Results The ultrasound results of 1 918 fetus demonstrated that the NT value was linearly increased with the increasing CRL.The 5th percentile was from 0.6 to 1.1 mm and the 95th percentile was from 1.7 to 2.3 mm at the CRL range from 45 to 84 mm.The followed-up results showed that 53 fetuses were found abnormality of development and in which 46 cases chose terminating the pregnancy.Conclusion The NT reference value should be dynamically set accroding to its dynanic change with NT.Patrt of serious fetus development abnormality could be screened by ultrasound at early pregnancy,which also could be a reliable basis for prenatal counseling.关键词
超声/胎儿/产前/颈项透明层/先天畸形Key words
Ultrasonography/Fetus/Prenatal/Nuchal translucency/Congenital abnormality引用本文复制引用
厉进,范雪梅,雷慧,胡伟..11～13+6周胎儿超声筛查在产前诊断中的临床价值[J].湖北医药学院学报,2016,35(4):391-393,3.基金项目
2013年深圳市南山区科创委科重点资助课题(南科研卫201103294号) （南科研卫201103294号）
