湖北医药学院学报2016，Vol.35Issue(4)：397-400,4.DOI:10.13819/j.issn.1006-9674.2016.04.016
十堰地区1 266例患者人乳头瘤病毒感染状况调查分析
Investigation and Analysis of Human Papilloma Virus Infection in 1 266 Patients in Shiyan Area
田彩霞 1刘堂鑫 2李莲 1王美钧 1颜敏 1兰勤 1瞿新1
作者信息
- 1. 湖北医药学院附属人民医院检验科,湖北十堰442000
- 2. 湖北医药学院附属太和医院骨Ⅱ科,湖北十堰442000
- 折叠
摘要
Abstract
Objective To investigate the infection status of human papilloma virus(HPV) in Shiyan area,and to investigate the regularity of distribution.Methods The genital tract secretion samples of 1 266 patients were detected for 21 kinds of HPV genotype using PCR and reverse dot blot technique,in which 1 149 cases were female and 117 cases were male.Results Total 549 cases were detected HPV infection in 1 266 samples,accounted for 43.36％,the infective rate of female was 41.78％ and the infective rate of male was 58.97％.The simple high-risk infection rate in female and male was 23.15％ and 20.51％,respectively.In HPV positive infected females,the top three high-risk subtypes was HPV-16(117 cases,accounted for 18.37％),HPV-58(93 cases,accounted for 14.60％) and HPV-52 (56 cases,accounted for 8.79％).In HPV positive infected males,the top three high-risk subtypes was HPV-16(18 cases,accounted for 19.35％),HPV-58 (12 cases,accounted for 12.90％) and HPV-31(9 cases,accounted for 9.68％).Conclusion The infective rate of HPV was high in Shiyan area,the main subtype of high-risk infection was HPV-16 and HPV-58,in particular the distribution regularity was significant differences between male and female.关键词
人乳头瘤病毒/基因分型/基因芯片Key words
Human papilloma virus/Genotyping/Gene chips引用本文复制引用
田彩霞,刘堂鑫,李莲,王美钧,颜敏,兰勤,瞿新..十堰地区1 266例患者人乳头瘤病毒感染状况调查分析[J].湖北医药学院学报,2016,35(4):397-400,4.
