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195例淀粉样变性肾病临床病理学相关因素分析

林峥 林春 江辉 郭春花 邓金秀

湖北医药学院学报2016,Vol.35Issue(6):561-565,5.
湖北医药学院学报2016,Vol.35Issue(6):561-565,5.DOI:10.13819/j.issn.1006-9674.2016.06.008

195例淀粉样变性肾病临床病理学相关因素分析

Logistics Regression Analysis of 195 Cases of Amyloidosis Nephropathy

林峥 1林春 1江辉 1郭春花 1邓金秀1

作者信息

  • 1. 福建医科大学附属龙岩第一医院肾内科,福建龙岩364000
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摘要

Abstract

Objective To study the influence factors of clinical pathological characteristics of amyloid nephropathy.Methods Total 195 patients with amyloidosis nephropathy from May 2006 to May 2015 in our department were selected,and the clinical data of them were retrospectively analyzed.According to the clinical manifestation,the patients was divided into proteinuria group,nephrotic syndrome group,renal insufficiency group.The relationship between pathological and clinical indexes was assessed by Logistic multivariate regression analysis.Results Thelevel of UPE in different stage of amyloidosis nephropathy had no statistical difference (P<0.05).Multivariate Logistic regression analysis showed HGB,Scr and eGFR levels were the risk factors of pathological in patients with amyloidosis nephropathy(P<0.05).Conclusion HGB,Scr and eGFR levels should be high concerned in the amyloidosis nephropathy patients.According to the change of HGB,Scr and eGFR,it was helpful to prognosis of some pathological character,such as amyloid deposits in the glomerular mesangial area,capillary basement membrane and small arteries,renal interstitial fibrosis and tubular atrophy,these could provide the theoretical foundation for early rationalization and standardized treatment.

关键词

肾病/淀粉样变性/病理学特征/相关因素

Key words

Amyloidosis nephropathy/Pathological characteristics/Related factor

引用本文复制引用

林峥,林春,江辉,郭春花,邓金秀..195例淀粉样变性肾病临床病理学相关因素分析[J].湖北医药学院学报,2016,35(6):561-565,5.

湖北医药学院学报

2096-708X

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