湖北医药学院学报2017，Vol.36Issue(1)：56-59,63,5.DOI:10.13819/j.issn.1006-9674.2017.01.013
全甲状腺切除+预防性患侧中央区淋巴结清扫术治疗甲状腺乳头状癌483例临床分析
Total Thyroidectomy Plus Prophylactic Ipsilateral Central Lymph Node Dissection for the Treatment of Papillary Thyroid Carcinoma:a Clinical Analysis for 483 Cases
周文波 1吴红伟 1沈丰 1孙少华 1胡洪生1
作者信息
- 1. 湖北医药学院附属东风医院甲状腺外科,湖北十堰442000
- 折叠
摘要
Abstract
Objective To analyze the clinical pathological features and the central lymph node metastasis of papillary thyroid carcinoma.To assess the safety and effectiveness of total thyroidectomy plus prophylactic ipsilateral central lymph node dissection in the treatment of papillary thyroid carcinoma.Methods A retrospective analysis of the clinical data 483 cases of papillary thyroid carcinomas operated from June 2012 to June 2015 in thyroid surgery of our treatment center after confirmed by surgery and pathology of papillary thyroid carcinoma.Results Among 483 cases of papillary thyroid carcinoma,32 cases (6.63％) were confirmed by pathology after operation.Whilst 163 cases(33.75％) were identified as the ipsilateral central lymph node metastasis.Unilateral multiple tumor lymph node metastasis rate was significantly higher than that in the unilateral solitary lesions (49.24％,30.72％),the difference has statistical significance (x2=13.877,P＜0.05).Single lesion,microcarcinoma and diameter greater than 1 cm papillary carcinoma in lymph node metastasis rate compared the difference was not statistically significant (x2 =0.966,P＞0.05).Multiple lesions,microcarcinoma and merge with tiny cancer patients with lymph node metastasis rate was significantly higher than that in the cases of tumor diameter was larger than 1 cm,full of tiny cancer cases of lymph node metastasis was higher than that with small cancer cases,the difference has statistical significance (x2 =7.066,P＜0.05).Temporary hypocalcemia incidence rate is 13.87％.The incidence of permanent parathyroid injury was 0.62％.The incidence of transient drinking water was 3.73％,no permanent water choke cough cases.Recurrentlaryngeal nerve palsy was 3.11％.Conclusion Papillary thyroid carcinoma is easy to occur in the early stage of central lymph node metastasis.Total thyroidectomy + preventive ipsilateral central lymph node dissection surgery is safe and effective.关键词
甲状腺肿瘤/甲状腺乳头状癌/淋巴结清扫/治疗Key words
Thyroid Neoplasms/Papillary thyroid carcinoma/Lymph node dissection/Therapy引用本文复制引用
周文波,吴红伟,沈丰,孙少华,胡洪生..全甲状腺切除+预防性患侧中央区淋巴结清扫术治疗甲状腺乳头状癌483例临床分析[J].湖北医药学院学报,2017,36(1):56-59,63,5.
