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高危晚期早产儿脑病临床特点及磁共振影像学评估

朱燕 张可 胡兰 肖蜜黎 李志华 陈超

中国当代儿科杂志2017,Vol.19Issue(5):567-571,5.
中国当代儿科杂志2017,Vol.19Issue(5):567-571,5.DOI:10.7499/j.issn.1008-8830.2017.05.018

高危晚期早产儿脑病临床特点及磁共振影像学评估

Clinical features and magnetic resonance imaging evaluation of encephalopathy in high-risk late preterm infants

朱燕 1张可 1胡兰 1肖蜜黎 1李志华 1陈超1

作者信息

  • 1. 复旦大学附属儿科医院新生儿科,上海 201102
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摘要

Abstract

Objective To investigate the risk factors, clinical features, and magnetic resonance imaging (MRI) changes of encephalopathy in high-risk late preterm infants. Methods Head MRI scan was performed for late preterm infants with high-risk factors for brain injury who were hospitalized between January 2009 and December 2014. The risk factors, clinical features, and head MRI features of encephalopathy in late preterm infants were analyzed. Results A total of 1007 late preterm infants underwent MRI scan, among whom 313 (31.1%) had imaging features in accordance with the features of encephalopathy of prematurity. Of all infants, 76.7% had white matter damage. There was no association between the development of encephalopathy and gestational age in late preterm infants, but the detection rate of encephalopathy gradually increased with the increasing birth weight (P<0.05). The logistic regression analysis showed that a history of resuscitation was an independent risk factor for encephalopathy of prematurity (P<0.01). Conclusions Encephalopathy of prematurity is commonly seen in high-risk late preterm infants, especially white matter damage. A history of resuscitation is an independent risk factor for encephalopathy in late preterm infants.

关键词

早产儿脑病/磁共振成像/危险因素/晚期早产儿

Key words

Encephalopathy of prematurity/Magnetic resonance imaging/Risk factor/Late preterm infant

引用本文复制引用

朱燕,张可,胡兰,肖蜜黎,李志华,陈超..高危晚期早产儿脑病临床特点及磁共振影像学评估[J].中国当代儿科杂志,2017,19(5):567-571,5.

中国当代儿科杂志

OA北大核心CSCDCSTPCDMEDLINE

1008-8830

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