中国全科医学2017，Vol.20Issue(8)：903-907,5.DOI:10.3969/j.issn.1007-9572.2017.08.003
代谢综合征及其各组分与骨质疏松性骨折的相关性研究
Correaltion of Metabolic Syndrome and Its Components with Osteoporotic Fractures
摘要
Abstract
Objective To explore the association of metabolic syndrome (MS) and its components with osteoporotic fractures in residents aged 40 or over in Guiyang.Methods The subjects enrolled in this study were 9 908 residents aged 40 or over in Yunyan district of Guiyang who participated in a survey of chronic diseases in 2011.A self-developed questionnaire was used to survey the subjects,which included gender,age,living habits,medical history and history of osteoporotic fractures.We measured the height,body weight,waist circumference,blood pressure,fasting plasma glucose (FPG),triglyceride (TG),high-density lipoprotein cholesterol (HDL-C) levels in the subjects.Results Of the 9 908 participants,23.87％ (2 365/9 908) had MS;17.65％ (1 749/9 908) had a history of osteoporotic fractures.There were no significant differences in age,proportions of residents without drinking tea and wine,ratio of residents drinking milk,BMI,prevalence rate for MS,waist circumference,systolic and diastolic blood pressure,FPG,TG,and HDL-C levels between male with a history of osteoporotic fractures and those without (P ＞ 0.05).Female with a history of osteoporotic fractures had older age,higher proportion of residents drinking milk,higher BMI and prevalence rate for MS,longer waist circumference,higher systolic pressure and TG,but lower HDL-C than those without (P ＜ 0.05).Multivariate Logistic regression analysis found that,after adjusting for confounding factors,such as age,drinking tea,wine and milk,and BMI,MS and its components had no relationship with osteoporotic fractures in male participants (P ＞ 0.05);MS [OR =1.224,95％ CI (1.065,1.407)],central obesity [OR =1.399,95％c CI (1.187,1.647)],elev ated level of TG [OR =1.273,95％ CI (1.121,1.446)],decreased level of HDL-C [OR =1.142,95％ CI (1.009,1.294)] were significantly associated with increased odds of osteoporotic fractures in female participants (P ＜0.05).Conclusion MS and its components of central obesity and dyslipidemia are risk factors for osteoporotic fractures in females aged 40 or over.关键词
骨质疏松症性骨折/代谢综合征X/危险因素/肥胖,腹部/血脂异常Key words
Osteoporotic fractures/Metabolic syndrome X/Risk factors/Obesity/abdominal/Dyslipidemias分类
医药卫生引用本文复制引用
曹婷,张巧,时立新,彭年春,张淼,张松,徐淑静..代谢综合征及其各组分与骨质疏松性骨折的相关性研究[J].中国全科医学,2017,20(8):903-907,5.基金项目
贵州省科技厅社会攻关计划[黔科合LG字(2011)016号] （2011）
贵州省优秀科技教育人才省长专项资金项目[黔省专合字(2010)82号] （2010）
