中国人兽共患病学报2017，Vol.33Issue(3)：236-240,5.DOI:10.3969/j.issn.1002-2694.2017.03.008
H6N1亚型禽流感病毒跨种属传播研究进展
Advance in cross species transmission of avian influenza virus H6N1 subtype
摘要
Abstract
Avian influenza virus H6N1 subtype has been circulating in aquatic bird and terrestrial bird,and is the most frequently detected subtype of influenza A virus in those hosts.Genetic analysis results suggested that this virus might be the progenitor of the highly pathogenic avian influenza H5N1 virus,as seven of eight gene segments of those viruses had a common source.As continuing evolution of H6N1,it could spread across species barriers to mammals and had strong infection ability in mice,swine and ferrets.Serological epidemiological survey showed that a few people were positive for H6 avian influenza virus antibody and then the world's first human infection with influenza virus H6N1 subtype was reported in May 2013.Therefore,with the expansion of the host range of the virus,gene mutation and gene reassortment of H6N1 virus can occur in these hosts,and then it may evolve into novel variant strain with infected human potential.关键词
甲型流感病毒/H6N1亚型/流行病学调查/感染/哺乳动物/人Key words
influenza A virus/H6N1 subtype/epidemiological investigation/infected/mammalian/human分类
医药卫生引用本文复制引用
孙增辉,朱银川,王熹婧,蒙远雁,张增峰..H6N1亚型禽流感病毒跨种属传播研究进展[J].中国人兽共患病学报,2017,33(3):236-240,5.基金项目
国家自然科学基金项目(Nos.31260033& 31660041)和广西自然科学基金项目(No.2013GXNSFAA019118)联合资助 （Nos.31260033& 31660041）
Supported by grants from the National Natural Science Foundation of China (Nos.31260033 & 31660041) and the Guangxi Natural Science Foundation (No.2013GXNSFAA019118) （Nos.31260033 & 31660041）
