中国人兽共患病学报2017，Vol.33Issue(3)：287-292,6.DOI:10.3969/j.issn.1002-2694.2017.03.018
链球菌毒力因子溶血素S的研究进展
Research progress on the virulence factors of Streptococcus hemolysin S
摘要
Abstract
Streptolysin S (SLS),one of the important virulence factors of Streptococcus,exist in several kinds of human and animal pathogenic bacterial,including Streptococcus pyogenes,Strepstococcus iniae and Streptococcus anginosus.SLS is a peptide toxin encoded by nine consecutive genes (sagA-sagⅠ).The functions of SLS include contributing pathogenic bacterium to pass through epithelial barrier,causing tissue damage,resisting to phagocytic clearance of host immune cells and interacting with other virulence factors.In addition,SLS as a signaling molecule of cell quorum sensing is involved in regulating the expression with other virulence factors.This paper summarized the structures and the biological functions of SLS in Streptococcus infection.关键词
化脓性链球菌/链球菌溶血素S/结构/致病作用Key words
Streptococcus pyogenes/streptolysin S/structure/pathogenic function分类
医药卫生引用本文复制引用
王虹,彭爽,陈德芳..链球菌毒力因子溶血素S的研究进展[J].中国人兽共患病学报,2017,33(3):287-292,6.基金项目
四川省教育厅项目(No.13ZB0279)资助 （No.13ZB0279）
Supported by the Science fund of Sichuan provincial Department of Education (No.13ZB0279) （No.13ZB0279）
