中国体外循环杂志2017，Vol.15Issue(1)：13-17,5.DOI:10.13498/j.cnki.chin.j.ecc.2017.01.04
应用心脑联合灌注策略改善复杂主动脉畸形患儿术后早期预后的临床研究
Clinical study on early postoperative prognosis of patients with complex aortic malformation with myocardial and cerebral perfusion strategy
摘要
Abstract
Objective To investigate and evaluate the effect of cerebral and myocardial perfusion (CMP) or only-regional cerebral perfusion (only-RCP) in pediatric underwent complicated aortic surgery.Methods From 2012 to 2014,one hundred and fifty one children with coarctation of aorta (CoA) or interrupted aortic arch combined with cardiac defects such as ventricular septal defect (VSD) or atrial septal defect (ASD) undergoing one-stage corrective surgery were included in this study.They were divided into two groups,CMP group (n=56) and only-RCP group (n=85),based upon the cardiopulmonary bypass (CPB) strategy.The surgery and CPB parameters,postoperative biochemical index,recovery situation,and postoperative complications of patients were recorded and compared between two groups.Results The bypass time,arrest time,operative time,cardiac ischemia time,the length of hospital stay and respiratory support time in CMP group were significantly shorter than those in only-RCP group.The level of biochemical index which can reflect the function of liver and kidney in CMP group was also lower than that in only-RCP group.Conclusion The modified perfusion strategy of CMP could provide better prognosis for children undergoing one-stage aortic arch surgery,and may reduce the length of hospital stay and the respiratory support time.关键词
心脑灌注/区域性脑灌注/主动脉弓手术国/儿童Key words
Cerebral and myocardial perfusion/Regional cerebral perfusion/Aortic arch surgery/Children引用本文复制引用
赵聪聪,刘晋萍,冯正义,赵举,胡金晓,崔勇丽,李守军,闫军..应用心脑联合灌注策略改善复杂主动脉畸形患儿术后早期预后的临床研究[J].中国体外循环杂志,2017,15(1):13-17,5.基金项目
国家自然科学基金资助项目专项(81370351) （81370351）
