中国体外循环杂志2017，Vol.15Issue(1)：38-41,4.DOI:10.13498/j.cnki.chin.j.ecc.2017.01.10
便携式体外生命支持系统离体和在体实验研究
Portable extracorporeal life support system in vitro and in vivo experiment
摘要
Abstract
Objective To explore the performance of a portable extracorporeal life support (PELS) system in vitro and in vivo.Methods In vitro,PELS system was tested for stable assessment;in vivo,12 female swine were randomized into experiment group (n=6) and control group (n=6).Cardiopulmonary bypass (CPB) was repectively established with PELS and RotaFlow with 4 L/min of flow for 6 h.The plasma free hemoglobin and platelet activation were evaluated before initial of CPB,every 2 hs in CPB and after terminated CPB.Results In vitro,experiments confirmed that the stability of PELS system was better than or equal to Maquet company Rotaflow system;in vivo,the plasma free hemoglobin was lower than 20 g/L and the platelet activation was lower than 10% after 6 h performance of PELS system.Conclusion The portable extracorporeal life support system conducts the reliable performance in vitro and in vivo.关键词
便携/体外生命支持/动物实验/体外实验Key words
Portable/Extracorporeal life support/In vivo/In vitro引用本文复制引用
刘宇,周圆圆,尹宗涛,李洪谊,王辉山..便携式体外生命支持系统离体和在体实验研究[J].中国体外循环杂志,2017,15(1):38-41,4.基金项目
2013年军队装备研制项目重大项目(ASY135001) （ASY135001）
2014年辽宁省建设产业技术创新体系示范工程医疗器械临床研究平台(2014305006) （2014305006）
