中国现代医学杂志2017，Vol.27Issue(7)：58-60,3.DOI:10.3969/j.issn.1005-8982.2017.07.013
获得性免疫缺陷综合征细菌性及肺孢子菌肺炎患者炎性指标比较
Comparison of inflammatory markers of bacterial pneumonia and Pneumocystis pneumonia in HIV/AIDS patients
王宇 1闻颖 1刘沛1
作者信息
- 1. 中国医科大学附属第一医院 传染科,辽宁 沈阳 110001
- 折叠
摘要
Abstract
Objective To seek a suitable marker for differentiating bacterial pneumonia from Pneumocystis pneumonia (PCP) in HIV/AIDS patients. Methods Inflammatory markers like C-reactive protein (CRP) and procalcitonin (PCT) were compared between HIV/AIDS patients with bacterial pneumonia and those with PCP, and the diagnostic value of each index was analyzed. Results There were 40 AIDS patients with bacterial pneumonia and 53 AIDS patients with PCP in our study. The difference was not significant between the two groups in temperature, white blood cell (WBC) or CRP ( p> 0.05). But the PCT level (ng/L) in the bacterial pneumonia group was significantly higher than rthat in the PCP group [(0.79 ± 1.25) vs (0.15 ± 0.10), p< 0.05]. In receiver operator characteristic (ROC) analysis, the area under curve (AUC) of PCT in diagnosing bacterial pneumonia was 0.853, the cut-off point was 0.205 (the sensitivity was 95%, and the specificity of 76%);while the AUC of CRP in diagnosing bacterial pneumonia was 0.563, the accuracy was low. Conclusions PCT might be a suitable marker for differentiating bacterial pneumonia from PCP in HIV/AIDS patients.关键词
降钙素原/C反应蛋白/HIV/AIDS/细菌性肺炎/肺孢子菌肺炎Key words
procalcitonin/C-reactive protein/HIV/AIDS/bacterial pneumonia/Pneumocystis
pneumonia分类
医药卫生引用本文复制引用
王宇,闻颖,刘沛..获得性免疫缺陷综合征细菌性及肺孢子菌肺炎患者炎性指标比较[J].中国现代医学杂志,2017,27(7):58-60,3.
