中国现代医学杂志2017，Vol.27Issue(7)：67-71,5.DOI:10.3969/j.issn.1005-8982.2017.07.016
动态血糖监测系统监测与其他葡萄糖检测方法的临床比较
Comparison between dynamic glucose monitoring system and other methods of blood glucose test
摘要
Abstract
Objective To investigate the relationships among dynamic glucose monitoring system (DGMS), glucose oxidase (GOD) and capillary glucose fingertip (CGF) and especially to analyze the difference and relation between DGMS and CGF under non-stable condition on the basis of stable condition of blood glucose. Methods GOD, CGF and DGMS were used to test blood glucose of 32 inpatients and outpatients from January to August 2015 and the difference and relation of these data were compared. There were 29 cases of type 2 diabetics and 3 cases of hypoglycemia in these patients. Results The value of DGMS (122) was lower than that of CGF (122); though the difference was only (0.11 ± 0.35) mmol/L, it was of significance ( p= 0.001). During oral glucose tolerance test (OGTT), the value of GOD was lower than that of DGMS at 0 min ( p= 0.000); from 30 min on the GOD value quickly exceeded DGMS value ( p= 0.001); and starting at 120 minutes the DGMS value rose faster than GOD, though it was still lower than the GOD value, they did not have marked difference (p >0.05). After merging 5 sets of data, the mean of GOD (160) had marked difference from that of DGMS (160) ( p= 0.000), which indicated that the glucose concentration of plasma was higher than that of tissue fluid. The correlation coefficient between CGF (122) and DGMS (122) was 0.989 ( p= 0.000) and that between GOD (160) and DGMS (160) was 0.911 ( p= 0.000). Conclusions Under stable state, there is a great relation between CGF and DGMS. On the basis of stable state, during OGTT or steamed bread meal tolerance test, with rapid increase of blood glucose, the glucose concentration of DGMS also rises in a trend similar to that of GOD. However, the reaction of DGMS is slower than that of GOD from the analysis of absolute value, and the blood glucose concentrations of the two methods do not have marked difference from 120 min on. This is the result of an unsteady state that reflects the true blood glucose. And the final comprehensive analysis of the five-points reveals that DGMS and GOD is in good correlation.关键词
葡萄糖/葡萄糖氧化酶法/指尖毛细血管血糖/动态葡萄糖监测系统Key words
glucose/glucose oxidase/capillary glucose fingertip/dynamic glucose monitoring system分类
医药卫生引用本文复制引用
关守萍,杨晓飞,康莹,苏恒,牛奔..动态血糖监测系统监测与其他葡萄糖检测方法的临床比较[J].中国现代医学杂志,2017,27(7):67-71,5.基金项目
云南省卫生和计划生育委员会医学后备人才项目(No:H-201614) （No:H-201614）
