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口蹄疫表位疫苗的研究进展

李世芳 邵军军 常惠芸

中国畜牧兽医2017,Vol.44Issue(2):396-401,6.
中国畜牧兽医2017,Vol.44Issue(2):396-401,6.DOI:10.16431/j.cnki.1671-7236.2017.02.014

口蹄疫表位疫苗的研究进展

Research Progress on the Epitope-based Vaccine against Foot and Mouth Disease

李世芳 1邵军军 1常惠芸1

作者信息

  • 1. 中国农业科学院兰州兽医研究所,家畜疫病病原生物学国家重点实验室,国家口蹄疫参考实验室,兰州730046
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摘要

Abstract

Foot and mouth disease (FMD) is caused by foot-and-mouth disease virus (FMDV) and affects cloven hoofed animals,it is an acute and potent infectious disease which has caused great loss in some regions.Up to now,people still use vaccines to prevent and control FMD which has become the the popular ways.Prepared by virus' antigen epitopes and carried with multiple epitopes and helper epitope,the epitope-based vaccine against FMD which has caught people's attention to it owing to it has high safety and is easy to be manipulated and controlled.In recent years,the research based on epitope of FMDV has made great progress.Now we review the latest progress of the FMDV epitopes and the epitope-based vaccine against FMD in this paper,in order to provide relevant preferences for the development of the vaccines with high security and efficiency.

关键词

口蹄疫/CTL表位/表位疫苗

Key words

FMD/cytotoxic T cell epitope/epitope-based vaccine

分类

农业科技

引用本文复制引用

李世芳,邵军军,常惠芸..口蹄疫表位疫苗的研究进展[J].中国畜牧兽医,2017,44(2):396-401,6.

基金项目

国家生猪产业体系项目(CARS-36-06B) (CARS-36-06B)

中国畜牧兽医

OA北大核心CSTPCD

1671-7236

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