中成药2017，Vol.39Issue(4)：710-713,4.DOI:10.3969/j.issn.1001-1528.2017.04.009
骨后康颗粒对老年股骨粗隆间骨折患者术后骨代谢指标的影响
Effects of Guhoukang Granules on bone metabolism indexes of the geriatric femoral intertrochanteric fracture
摘要
Abstract
AIM To observe the effects of Guhoukang Granules (Eucommiae Cortex,Dipsaci Radix,Corni Fructus,etc.) on bone metabolism indexes of the geriatric femoral intertrochanteric fracture.METHODS A total of eighty patients meeting the inclusion criteria,cured with fixed operation of proximal femoral anti-rotation nail and given basic care,were divided randomly and equally into two groups:experiment group (Guhoukang Granules ) and control group (calcium carbonate D3 tablets).Three months made a course.Osteocalcin (OC),calcitonin (CT),bone-specific alkaline phosphatase (BALP),total procollagen type 1 aminoterminal propeptide (tPINP),β isomer of the C-terminal telopeptide of type Ⅰ collagen (β-CTX),and intact parathyroid hormone (iPTH),were examined before and after three months,respectively.RESULTS There were no significant statistical difference in the levels of OC,CT,BALP,tPINP,β-CTX and iPTH before operation in both groups.The levels of OC,CT,BALP,tPINP in the experiment group obviously increased and the levels of β-CTX,iPTH markedly decreased after the operation,and were better than those in the experiment group pre-operation and in the control group after the operation.The control group had no improvement in bone metabolism indexes pre-and post-operation.CONCLUSION Guhoukang Granules can improve bone metabolism of the geriatric femoral intertrochanteric fracture and facilitate the recovery of the fracture.关键词
骨后康颗粒/老年股骨粗隆间骨折/骨代谢指标Key words
Guhoukang Granules/geriatric femoral intertrochanteric fracture/bone metabolism indexes分类
医药卫生引用本文复制引用
彭印文,陈秋风,张志辉..骨后康颗粒对老年股骨粗隆间骨折患者术后骨代谢指标的影响[J].中成药,2017,39(4):710-713,4.基金项目
广东省佛山市科技局医学类攻关项目(2015AB002493) （2015AB002493）
