摘要
Abstract
Objective To investigate the therapeutic effect of Ziyin Huoxue decoction and entecavir in the treatment of decompensated hepatitis B cirrhosis.Methods 98 cases of chronic hepatitis B cirrhosis treated at our hospital from January,2012 to January,2014 were randomly divided into a control group and a treatment group,49 cases for each group.The control group was given symptomatic support treatment and took entecavir;in addition,the treatment group was treated with Ziyin Huoxue decoction.3 months was 1 treatment course.Both groups were treated 3 courses.The patients were followed up.The liver fibrosis indicators,hepatitis B virus markers,and liver function indicators were compared between these two groups.Results The ALT recovery rates were 73.5％,83.7％,89.8％,and 91.8％ in the treatment group,which were significantly higher than those in the control group,with statistical differences (all P ＜ 0.05).The HBV DNA negative rates were 73.5％,79.6％,85.7％,and 91.8％ in the treatment group,which were significantly higher than those in the control group,with statistical differences (all P ＜ 0.05).The total efficacy was 95.9％ in the treatment group and 59.2％ in the control group,with a statistical difference (P ＜ 0.05).The obviously effective rate was 73.5％ in the treatment group and 26.5％ in the control group,with a statistical difference (P ＜ 0.05).The HA,procollagen type Ⅲ,and type Ⅳcollagen were better in the treatment group than in the control group,with statitical differences (all P ＜ 0.05).Conclusions Ziyin Huoxue decoction and entecavir in the treatment of decompensated hepatitis B cirrhosis can significantly improve the patients' clinical symptoms and improve clinical curative effect and is safe and reliable,so it is worth being clinically generalized.关键词
滋阴活血汤/恩替卡韦/代偿期乙型肝炎肝硬化Key words
Ziyin Huoxue decoction/Entecavir/Decompensated hepatitis B cirrhosis
