临床与病理杂志2017，Vol.37Issue(2)：403-407,5.DOI:10.3978/j.issn.2095-6959.2017.02.030
中性粒细胞胞外诱捕网在动脉粥样硬化中的研究进展
Research progress of neutrophil extracellular traps in atherosclerosis
摘要
Abstract
It has become a consensus in the field of cardio-cerebrovascular disease that atherosclerosis is an inflammatory response disease,and inflammation cells involved in atherosclerotic are varied,including mononuclearmacrophages,dendritic cells,T lymphocytes and neutrophils,etc.Neutrophil extracellular traps (NETs) are mesh structure released by activated neutrophils.They have diverse biological activities,such as anti-inflammatory and proinflammatory effect,procoagulant activity.They also participate in pathological processes of many kinds of diseases.A number of studies found that neutrophils can be activated by some stimulating factor and release NETs.NETs have cytotoxic and pro-thrombotic effects,and the ability to interact with macrophages,they play an important role in atherosderosis pathology as a link between inflammation and thrombosis.关键词
中性粒细胞胞外诱捕网/动脉粥样硬化/炎症反应Key words
neutrophil extracellular traps/atherosclerosis/inflammatory response引用本文复制引用
吕强..中性粒细胞胞外诱捕网在动脉粥样硬化中的研究进展[J].临床与病理杂志,2017,37(2):403-407,5.基金项目
武警总医院院级课题(WZ2015013).This work was supported by Hospital Level Scientific Research Project Foundation in General Hospital of Chinese People's Armed Police Force (WZ2015013),P.R.China. （WZ2015013）
