摘要
Abstract
Objective:To observe the clinical curative effect of TCM therapy combined with epalrestat in treatment of diabetic peripheral neuropathy patients.Methods:80 cases of diabetic peripheral neuropathy were randomly divided into the observation group and the control group with 40 cases in each group.The control group was given epalrestat,3 times daily,50mg each time,oral.The observation group was treated with self-made Huoxue Huayu Tongluo Tang based on the control group.After 12 weeks of treatment,the clinical efficacy,symptom improvement,SOD,blood glucose and glycosylated hemoglobin levels were compared between the two groups.Results:After treatment,the effective rate of observation group was 82.5 ％,the control group was 67.5％,and the difference was statistically significant between the two groups (P ＜ 0.05).The improvement rate of numbness,pain and paresthesia in the observation group was higher than that in the control group (P ＜ 0.05).After treatment,SOD of the observation group was significantly higher than that of the control group (P ＜ 0.05);fasting blood glucose,postprandial blood glucose,glycosylated hemoglobin of the two groups after treatment were significantly lower than before treatment (P ＜ 0.05),and there was no significant difference between the two groups after treatment.Conclusion:TCM therapy combined with epalrestat treatment of diabetic peripheral neuropathy has significant curative effect.关键词
糖尿病周围神经病变/中医综合疗法/针灸疗法/活血化瘀通络汤/依帕司他/超氧化物歧化酶/中西医结合Key words
diabetic peripheral neuropathy/TCM therapy/acupuncture therapy/Huoxue Huayu Tongluo Tang/epalrestat/superoxide dismutase/combination of traditional Chinese and Western medicine分类
医药卫生
