中医药导报2017,Vol.23Issue(7):90-94,5.
中药灌肠联合美沙拉嗪口服治疗溃疡性结肠炎的系统评价
A Systematic Review of Traditional Chinese Medicine Enema Combined with Mesalazine in Treating Ulcerative Colitis
摘要
Abstract
Objective:To evaluate the therapeutic effect of Traditional Chinese medicine enema combined with mesalazine in treating Ulcerative colitis.Methods:Databases as CNKI,WANGFANG,CBM,VIP,PubMed,Cochrane Library (The search time was April 2016),relevant journals,and the literature of RCTs were all enrolled.The quality of RCTs was assessed by using Jadad scores,meta-analyses were performed with Review Manager 5.3 software.Results:There were twenty-two articles enrolled.And 1579 patients were included.The result of Meta-analyses showed that treatment group could improve the effective rate [RR=1.25,95% CI (1.19,1.31),P<O.00001],reduce the recurrence rate [RR=0.45,95% CI (0.26,0.77),P=0.003],and reduce the Erythrocyte sedimentation rate [WMD=-5.36,95% CI (-8.10,-2.61),P=0.0001].Conclusion:The combination of TCM enema and mesalazine in treating Ulcerative colitis is better than only using mesalazine.关键词
溃疡性结肠炎/中药灌肠/美沙拉嗪/系统评价/Meta分析Key words
ulcerative colitis/Traditional Chinese Medicine enema/Mesalazine/systematic review/Meta-analyses分类
医药卫生引用本文复制引用
吴驻林,张思容,王露,彭立生..中药灌肠联合美沙拉嗪口服治疗溃疡性结肠炎的系统评价[J].中医药导报,2017,23(7):90-94,5.基金项目
深圳市知识创新计划项目(JCYJ20150401163247231) (JCYJ20150401163247231)