临床肝胆病杂志2017，Vol.33Issue(3)：409-412,4.DOI:10.3969/j.issn.1001-5256.2017.03.001
肝纤维化的发病机制及治疗新靶点
Pathogenesis and new therapeutic targets of liver fibrosis
张伟 1贾继东1
作者信息
- 1. 首都医科大学附属北京友谊医院肝病中心,北京100050
- 折叠
摘要
Abstract
In recent years,the basic research on liver fibrosis has been progressed rapidly.This article briefly reviews the cellular and molecular mechanisms of liver fibrosis,including the origin of myofibroblasts,immune regulation,autophagy,and epigenetic regulation,and introduces several new therapeutic targets.More and more evidences show that successful removal of causes is the most important antifibrotic therapy.At present,although the antifibrotic drugs acting on different targets have been emerging,most of them are still in the early stage of research and development,and well-designed clinical trials are needed to confirm their clinical efficacy.关键词
肝硬化/治疗/述评Key words
liver cirrhosis/therapy/editorial分类
医药卫生引用本文复制引用
张伟,贾继东..肝纤维化的发病机制及治疗新靶点[J].临床肝胆病杂志,2017,33(3):409-412,4.
