临床肝胆病杂志2017，Vol.33Issue(3)：445-450,6.DOI:10.3969/j.issn.1001-5256.2017.03.009
肝纤维化新型分子诊断标志物
Novel molecular diagnostic markers for liver fibrosis
杜静华 1南月敏1
作者信息
- 1. 河北医科大学第三医院中西医结合肝病科,石家庄050051
- 折叠
摘要
Abstract
Liver fibrosis is an important pathological stage for the progression of chronic liver diseases to liver cirrhosis.Timely and accurate assessment of fibrosis degree plays an important role in guiding the treatment of chronic liver diseases.With the development of molecular biology techniques and wide application of molecular diagnostic techniques,the measurement of novel serum molecular diagnostic markers may contribute to the early diagnosis and precise treatment of liver fibrosis.A number of novel serum molecular markers with a diagnostic value have been identified,including fibroblast factor,matrix metalloproteinases and their inhibitors,extracellular matrix-related markers,and non-coding RNAs.In addition,genomics,proteomics,and metabolomics also have certain diagnostic values.关键词
肝硬化/生物学标记/诊断Key words
liver cirrhosis/biological markers/diagnosis分类
医药卫生引用本文复制引用
杜静华,南月敏..肝纤维化新型分子诊断标志物[J].临床肝胆病杂志,2017,33(3):445-450,6.
