临床肝胆病杂志2017，Vol.33Issue(3)：548-552,5.DOI:10.3969/j.issn.1001-5256.2017.03.034
GGT与PLT比值指数对慢性乙型肝炎肝纤维化的诊断价值
Association between γ-glutamyl transpeptidase-to-platelet ratio and hepatic fibrosis in patients with chronic hepatitis B
摘要
Abstract
Early and accurate diagnosis of hepatic fibrosis and application of antiviral therapy are the key to improving the prognosis of patients with chronic hepatitis B (CHB).Liver biopsy and transient elastography cannot be widely used for the diagnosis of hepatic fibrosis in clinical practice,and therefore,the serological diagnostic model has become a hot research topic in recent years.This article introduces a new serological diagnostic model,γ-glutamyl transpeptidase-to-platelet ratio (GPR),which has a high value in the diagnosis of hepatic fibrosis in CHB patients;however,the accuracy of GPR varies between different populations and different areas.GPR is also an excellent predictor for the prognosis of hepatitis B-associated liver cancer.It is pointed out that GPR has a promising future in the diagnosis of hepatic fibrosis in CHB patients,but due to a lack of clinical research data on GPR,further studies are needed to support its application in China.关键词
肝炎,乙型,慢性/肝硬化/γ-谷氨酰转移酶/血小板/综述Key words
hepatitis B, chronic/liver cirrhosis/gamma-glutamyltransferase/blood platelets/review分类
医药卫生引用本文复制引用
董菁菁,郭宏华..GGT与PLT比值指数对慢性乙型肝炎肝纤维化的诊断价值[J].临床肝胆病杂志,2017,33(3):548-552,5.基金项目
吉林省科技项目资助(20140311092YY) （20140311092YY）
