临床与实验病理学杂志2017，Vol.33Issue(3)：278-282,5.DOI:10.13315/j.cnki.cjcep.2017.03.010
子宫内膜样腺癌合并盆腔淋巴结淋巴管肌瘤病的临床病理分析
Endometrial endometrioid adenocarcinoma with lymphangiomyomatosis of pelvis lymph node: clinicopathological analysis
朱琳 1周莉 1秦东瑞 1迟亚松 2马广贞1
作者信息
- 1. 山东省聊城市第二人民医院病理科 252601
- 2. 山东省聊城市第二人民医院妇科 252601
- 折叠
摘要
Abstract
Purpose To study the clinicopathological features of lymphangiomyomatosis (LAM) of pelvis lymph node.Methods A patient with endometrial endometrioid adenocarcinoma and LAM was analyzed including clinical data and pathological features.HE and immunohistoehemistry of EnVision stainings were used,and the literatures were reviewed.Results Well-moderately differentiated endometrioid adenocarcinoma could be observed in the endometrium.Proloferation of LAM cells were seen in the capsule and medulla of the pelvic lymph node.The LAM cell was spindle,epitheliod and polygonal cells with oxyphilic or clear cytoplasm which arranged surrounding lacunes.The LAM cells showed no atypia and mitosis could not seen.The tumor cells showed diffusely positive for SMA,Caldesmon,desmin,vimentin,ER and PR,the cells lining the lacunes were positive for CD34 and D2-40.The epitheliod cells were positive for HMB-45 and negative for Melan-A.The Ki-67 immunostaining showed a proliferation index of ＜ 1％.Conclusion LAM is an uncommon neoplastic multisystem disease that affects the lungs mostly.Endometrial endometrioid adenocarcinoma with LAM of pelvic lymph node is extremely rare.The diagnosis can be made according to the histological characteristics and immunohistochemical features.Moreover this conclusion will provide the clinicopathological materials for the future study about LAM.关键词
子宫内膜肿瘤/淋巴管肌瘤病/淋巴管肌瘤/盆腔淋巴结Key words
endometrial neoplasm/lymphangiomyomatosis/lymphangiomyoma/pelvic lymph node分类
医药卫生引用本文复制引用
朱琳,周莉,秦东瑞,迟亚松,马广贞..子宫内膜样腺癌合并盆腔淋巴结淋巴管肌瘤病的临床病理分析[J].临床与实验病理学杂志,2017,33(3):278-282,5.
