摘要
Abstract
Objective To explore the risk factors of hemorrhagic transformation in patients with acute cerebral ischemia (ACI) of middle cerebral artery (MCA) blood supply area.Methods Clinical data of 570 patients with ACI of MCA were collected.Using SPSS 21.0 statistical software,risk factors of hemorrhagic transformation in ACI were analized.Single factor Logistic regression analysis was done first,and then,the factors that with statistical significance were included in the multivariate Logistic regression analysis.Results Factors included in the univariate analysis were atrial fibrillation,fasting blood glucose levels,early infarct size on CT,cardiac embolism infarct,NIHSS score,male,low density lipoprotein cholesterol,and baseline platelet count.Multivariate Logistic regression analysis showed that 1/3 MCA≤ early visible hypodensity on initial brain CT scan ＜ 2/3 MCA(OR=3.671,95％CI =1.780-7.573),early visible hypodensity on initial brain CT scan≥2/3 MCA (OR-3.366,95％ CI =1.378-8.225),atrial fibrillation (OR =3.376,95 ％ CI =2.070-5.505),fasting blood glucose levels (OR =1.175,95 ％ CI =1.074-1.286),and NIHSS≥10 (OR=1.890,95％CI=1.123-3.180) were risk factors for hemorrhagic transformation in ACI.Conclusion An early infarction area larger than 1/3 of middle cerebral artery blood supply area on initial brain CT scan,atrial fibrillation,fasting blood glucose levels,and NIHSS≥10 are the independent risk factors for hemorrhagic transformation in patients with acute cerebral ischemia.关键词
脑梗死/出血/危险因素Key words
brain infarction/hemorrhage/risk factors分类
医药卫生
